![]() ![]() Pruritis: Etiology and patient evaluation. In: Andrews' Diseases of the Skin: Clinical Dermatology. Pruritis: Therapies for generalized pruritus. Prolonged itching and scratching can increase the intensity of the itch, possibly leading to skin injury, infection and scarring. It might disturb your sleep or cause anxiety or depression. Itchy skin that is severe or lasts more than six weeks can affect the quality of your life. Sometimes the cause of the itching can't be determined. Also, reactions to certain medicines, such as narcotics to treat pain (opioids) can cause itchy skin. Sometimes a substance, such as poison ivy or cosmetics, causes an allergic reaction. Wool, chemicals, soaps and other things can irritate the skin and cause rashes and itching. Examples include anxiety, obsessive-compulsive disorder and depression. Examples include multiple sclerosis, pinched nerves and shingles (herpes zoster). ![]() Itching on the whole body might be a symptom of an underlying illness, such as liver disease, kidney disease, anemia, diabetes, thyroid problems and certain cancers. Examples include dry skin (xerosis), eczema (dermatitis), psoriasis, scabies, parasites, burns, scars, insect bites and hives. You may also need to see a doctor who specializes in internal medicine (internist) to check for other diseases. If the condition persists for three months despite treatment, see a dermatologist to be evaluated for skin disease.
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